We were having issues with slow TX/RX between two sites over a PPTP VPN connection. I found that the issue was MTU mismatches and used this command to fix it:
sudo ifconfig ppp0 mtu 1492

Just need to mention that this did not really do much to fix the speed issue and in the end we decided on OpenVPN which is awesome!

Reference:
http://jimiz.net/2011/04/permanent-mtu-settings-ppp0-ubuntu/#axzz35jpbw3cp

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